Upon completing Module 1, students will be able to:  

• Explain the fundamental concepts of genetic variants and their causal relationship to liver disease susceptibility and progression.

• Understand the genome-wide association study (GWAS) design and interpret its results.  

• Evaluate the biological insights learned from common genetic variants and assess their implications for therapeutic targets and risk prediction. 

• Explain key concepts of epigenomics (e.g., DNA methylation, histone modifications, chromatin accessibility) within the context of liver biology and pathology.  

• Design experimental approaches for investigating genetic and epigenetic alterations in liver diseases. 

• Critically assess the strengths, limitations, and clinical relevance of current genomics and epigenomics methodologies.